The topics covered in this chapter can be summarized as follows:
- An introduction to the general group of RNA viruses known as coronaviruses with emphasis on the general structure of such viruses
- A summary of how the virus’ surface spike protein mediates SARS-CoV-2 entry into human cells by binding to the ACE2 (Angiotensin-converting enzyme 2) receptor.
- A list of some of the genes Implicated in Severe COVID-19 Infection in Humans
- A discussion of the approaches for Vaccine Development Against SARS‐Cov‐2