Chapter 12 Summary

The topics covered in this chapter can be summarized as follows:

  • There are different types of chromosome maps: genetic (recombination), cytogenetic (metaphase chromosome), and physical maps.
  • Recombination frequency is usually proportional to the distance between loci, and so recombination frequencies can be used to create genetic maps.
  • Chromosomes can be distinguished cytologically based on their length, centromere position, and banding patterns when stained with dyes.
  • Single clones can be restriction mapped and then combined into a contig that represents a larger region of DNA, ultimately the whole chromosome.
  • The ultimate physical map is the DNA sequence of the whole chromosome or genome.

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Open Genetics by Natasha Ramroop Singh, Thompson Rivers University is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.

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