The topics covered in this chapter can be summarized as follows:
- Recombination is defined as any process that results in gametes with combinations of alleles that were not present in the gametes of a previous generation.
- The recombination frequency between any two loci depends on their relative chromosomal locations.
- Unlinked loci show a maximum 50% recombination frequency.
- Loci that are close together on a chromosome are linked and tend to segregate with the same combinations of alleles that were present in their parents.
- Crossovers are a normal part of most meioses, and allow for recombination between linked loci.
- Measuring recombination frequency is easiest when starting with pure-breeding lines with two alleles for each locus, and with suitable lines for test crossing.