Chapter 5 Summary

The topics covered in this chapter can be summarized as follows:

• The purpose of performing Complementation testing is to determine whether two mutants are the result of mutation of the same gene (allelic mutations), or if each mutant is caused by mutation of a different gene (non-allelic mutations).
• Complementation group contains mutants that cannot complement each other (allelic mutations) and therefore are assumed to have mutations at the same gene loci.
• Transformation rescue refers to the incorporation of recombinant DNA molecule that contains a gene that is able to complement the mutated gene in another organism.